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IL17C

interleukin 17C

Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.

Gene Name: interleukin 17C
Family/Subfamily: Interleukin
Synonyms: IL17C, CX2, Cytokine CX2, Interleukin 17C, IL-17C, IL-21, Interleukin-17C
Target Sequences: NM_013278 NP_037410.1 Q9P0M4

☰ Filters
Antibodies (38)
ELISA Kits (12)
Proteins (7)
Custom (1)
Over-Expression Lysate (2)
Primary (38)
Recombinant (5)
Sandwich (9)
Sandwich CLIA (2)
IL17C (57)
Human (35)
Mouse (17)
Rat (1)
Primate (1)
IHC (5)
IHC-P (2)
WB (35)
Flo (1)
ELISA (7)
IP (1)
Peptide-ELISA (2)
rabbit (34)
mouse (2)
goat (1)
rat (1)
IgG (13)
IgG1,k (1)
IgG2a (1)
monoclonal mc (2)
polyclonal pc (36)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (9)
APC (2)
APC Conjugated (3)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (19)
aa36-187 (8)
aa7-159 (8)
aa80-130 (1)
No (57)
Cell Culture Supernatants (7)
Cell Lysates (3)
Plasma (11)
Serum (11)
Tissue Homogenates (3)
GST (1)
His, N-Terminal (1)
His-GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
IL17C Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using IL17C Polyclonal Antibody at dilution of 1:50.
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IL17C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL17C Antibody - Goat Anti-IL17C (aa160-172) Antibody (0.3µg/ml) staining of Human Lymph Node lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence.
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IL17C Goat anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
IL17C ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
1.37 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$871
Select
IL17C Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, Flo
Unconjugated
100 µg/$872
IL17C Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IL17C Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IL17C Mouse anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$705
IL17C Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using IL17C Polyclonal Antibody at dilution of 1:50.
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IL17C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
IL17C ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
IL17C Protein - Recombinant Interleukin 17C By SDS-PAGE
Select
E. coli
His-GST, N-terminus
20.7 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
IL17C Antibody - Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:200.
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IL17C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
IL17C Antibody - Western blot - Anti-IL17C Picoband antibody
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IL17C Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
IL17C Antibody - Western blot - Anti-IL17C Picoband antibody
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IL17C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
IL17C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P
Unconjugated
100 µg/$357
Select
IL17C Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
IL17C Antibody - Western blot of recombinant IL17C.
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IL17C Rabbit anti-Mouse Polyclonal (aa7-159) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
IL17C Antibody - Western blot of recombinant IL17C.
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IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
IL17C Antibody - Western blot of recombinant IL17C.
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IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
IL17C Antibody - Western blot of recombinant IL17C.
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IL17C Rabbit anti-Mouse Polyclonal (aa7-159) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
IL17C Antibody - Fig-1: Western blot analysis of IL-17C. Anti-IL-17C antibody was tested at 2 µg/ml on A549 cell lysate.
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IL17C Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
25 µg/$288; 100 µg/$414
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IL17C Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
Select
IL17C Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
IL17C Antibody - Western blot analysis of extracts of various cell lines, using IL17C antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 20s.
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IL17C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
IL17C Antibody - Western Blot: IL17C Antibody - Analysis of IL-17C using IL17C antibody. THP1 cell lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of IL17C antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
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IL17C Rabbit anti-Human Polyclonal (aa80-130) Antibody
Human, Primate
WB
Unconjugated
0.1 mg/$386
IL17C Antibody
Select
IL17C Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
IL17C Antibody - Western blot of recombinant IL17C.
Select
IL17C Rabbit anti-Human Polyclonal (aa36-187) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561
Viewing 1-25 of 57 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).