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Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
Gene Name: | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
Synonyms: | LSM5, YER146W |
Target Sequences: | NM_012322 NP_036454.1 Q9Y4Y9 |
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