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Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Gene Name: | hes-related family bHLH transcription factor with YRPW motif 1 |
Synonyms: | HEY1, BHLHb31, CHF2, CHF-2, HERP2, HRT1, HESR-1, HHRT1, HRT-1, OAF1, HESR1 |
Target Sequences: | NM_012258 NP_036390.3 Q9Y5J3 |
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