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Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.
Gene Name: | phenylalanyl-tRNA synthetase 2, mitochondrial |
Synonyms: | FARS2, COXPD14, DJ236A3.1, DJ520B18.2, FARS1, Phenylalanyl-tRNA synthetase, HSPC320, Phenylalanine translase, PheRS |
Target Sequences: | NM_006567 NP_006558.1 O95363 |
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