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CD2BP2 is a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Gene Name: | CD2 (cytoplasmic tail) binding protein 2 |
Synonyms: | CD2BP2, CD2 tail-binding protein 2, KIAA1178, FWP010, Snu40, U5 snRNP 52K protein, U5-52K, PPP1R59, LIN1 |
Target Sequences: | NM_006110 NP_006101.1 O95400 |
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