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RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Gene Name: | polypyrimidine tract binding protein 3 |
Synonyms: | PTBP3, ROD1, Regulator of differentiation 1 |
Target Sequences: | NM_005156 NP_005147.3 O95758 |
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