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Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Gene Name: | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
Synonyms: | PRKRIR, Death-associated protein 4, p58IPK-interacting protein, p52rIPK, THAP0, DAP4 |
Target Sequences: | NM_004705 NP_004696.2 O43422 |
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