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Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis.
Gene Name: | calpain 11 |
Family/Subfamily: | Protease , Cysteine C2 |
Synonyms: | CAPN11, Calpain11, CANP 11, Calpain 11, Calpain-11 |
Target Sequences: | NM_007058 NP_008989.2 Q9UMQ6 |
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