Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Gene Name: | glycine dehydrogenase (decarboxylating) |
Synonyms: | GLDC, GCSP, Glycine decarboxylase, HYGN1, GCE, Glycine dehydrogenase, NKH |
Target Sequences: | NM_000170 NP_000161.2 P23378 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.