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Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2.
Gene Name: | glutamate receptor, ionotropic, kainate 2 |
Family/Subfamily: | Ion Channel , Glutamate receptor - ionotropic (NMDA receptor) |
Synonyms: | GRIK2, BA487F5.1, GluR-6, Glur5-7, GLUR6, Glutamate receptor form A, Glutamate receptor form B, EAA4, Glutamate receptor form C, GLR6, GLUK6, Glutamate receptor form E, MRT6, GluK2, Glutamate receptor 6, Glutamate receptor form D |
Target Sequences: | NM_021956 NP_068775.1 Q13002 |
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