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Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Gene Name: | breast cancer anti-estrogen resistance 1 |
Synonyms: | BCAR1, CAS, CAS1, CRKAS, CASS1, CRK-associated substrate, p130Cas |
Target Sequences: | NM_014567 NP_055382.2 P56945 |
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