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FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing.
Gene Name: | follicle stimulating hormone receptor |
Family/Subfamily: | GPCR , Glycoprotein hormone |
Synonyms: | FSHR, FSHRO, Ovarian dysgenesis 1, FSH receptor, FSH-R, LGR1, ODG1 |
Target Sequences: | NM_000145 NP_000136.2 P23945 |
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