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Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
Gene Name: | interferon stimulated exonuclease gene 20kDa |
Synonyms: | ISG20, CD25, HEM45 |
Target Sequences: | NM_002201 NP_002192.2 Q96AZ6 |
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