Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).
Gene Name: | nucleoporin 153kDa |
Family/Subfamily: | Nucleoporin |
Synonyms: | NUP153, 153 kDa nucleoporin, N153, Nucleoporin 153kD, Nucleoporin 153kDa, HNUP153, Nucleoporin Nup153 |
Target Sequences: | NM_005124 NP_005115.2 P49790 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.