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Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na+ channels: SCNN1A/ENAC, K+ channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase.
Gene Name: | serum/glucocorticoid regulated kinase 2 |
Family/Subfamily: | Protein Kinase , SGK |
Synonyms: | SGK2, DJ138B7.2, H-SGK2, Hsgk2 |
Target Sequences: | NM_016276 NP_057360.2 Q9HBY8 |
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