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PDCD2 is a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
Gene Name: | programmed cell death 2 |
Synonyms: | PDCD2, Programmed cell death 2, Zinc finger protein Rp-8, RP8, ZMYND7 |
Target Sequences: | NM_002598 NP_002589.2 Q16342 |
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