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PRUNE is a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants.
Gene Name: | prune exopolyphosphatase |
Synonyms: | PRUNE, BMCC1, HPrune, HTCD37, KIAA0367, Protein prune homolog, Prune homolog (Drosophila), DRES-17, DRES17 |
Target Sequences: | NM_021222 AAK00593.1 Q86TP1 |
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