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CTH / Cystathionase

cystathionase (cystathionine gamma-lyase)

Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: CTH, Cysteine-protein sulfhydrase, Cysteine desulfhydrase, Cystathionine gamma-lyase, Homoserine dehydratase, Gamma-cystathionase, Homoserine deaminase
Target Sequences: NM_001902 NP_001893.2 P32929

Publications (1)

1
Clear cell and endometrioid carcinomas: are their differences attributable to distinct cells of origin?. Dawn R Cochrane, Basile Tessier-Cloutier, Katherine M Lawrence, Tayyebeh Nazeran, Anthony N Karnezis, Clara Salamanca, Angela S Cheng, Jessica N McAlpine, Lien N Hoang, C Blake Gilks, David G Huntsman. The Journal of pathology. 2017 September;243:26-36. [Full Text Article] [PubMed:28678427]

☰ Filters
Antibodies (62)
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CTH / Cystathionase (83)
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CTH / Cystathionase Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CTH / Cystathionase Mouse anti-Human Monoclonal (1E12) Antibody
Dog, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CTH / Cystathionase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
CTH / Cystathionase Antibody - Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
WB
Unconjugated
100 µl/$424
CTH / Cystathionase Antibody - Immunoperoxidase of monoclonal antibody to CTH on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
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CTH / Cystathionase Mouse anti-Human Monoclonal (S51) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
CTH / Cystathionase Antibody - CTH monoclonal antibody (M01), clone 4E1-1B7. Western blot of CTH expression in human liver.
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CTH / Cystathionase Mouse anti-Human Monoclonal (4E1-1B7) Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$423
CTH / Cystathionase Antibody - Anti-CTH antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CTH / Cystathionase Mouse anti-Human Monoclonal (2D6) Antibody
Dog, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CTH / Cystathionase Antibody - CTH antibody. IHC(P): Human Liver Cancer Tissue.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa316-331) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CTH / Cystathionase Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using CTH Antibody at dilution of 1:100
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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CTH / Cystathionase Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$351
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$331
CTH / Cystathionase Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CTH / Cystathionase Mouse anti-Human Monoclonal (Carrier-free) (1.00E+12) Antibody
Dog, Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CTH / Cystathionase Antibody - Anti-CTH antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CTH / Cystathionase Mouse anti-Human Monoclonal (Carrier-free) (2D6) Antibody
Dog, Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CTH / Cystathionase Antibody - CTH antibody CTH(cystathionase (cystathionine gamma-lyase)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa281-330) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
CTH / Cystathionase Antibody - CTH antibody CTH(cystathionase (cystathionine gamma-lyase)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa281-330) (HRP) Antibody
Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
CTH / Cystathionase Antibody - CTH antibody CTH(cystathionase (cystathionine gamma-lyase)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa281-330) (Biotin) Antibody
Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
CTH / Cystathionase Antibody - CTH antibody CTH(cystathionase (cystathionine gamma-lyase)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Human Polyclonal (aa281-330) (FITC) Antibody
Human, Chimpanzee, Orangutan, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
CTH / Cystathionase Antibody - Western blot analysis of extracts of various cell lines, using CTH antibody.
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
CTH / Cystathionase Antibody - Western blot analysis of CTH using HuvEc whole cells lysates
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CTH / Cystathionase Antibody - Western blot of recombinant CTH.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTH / Cystathionase Rabbit anti-Mouse Polyclonal (aa14-224) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CTH / Cystathionase Antibody - Western blot of CTH antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
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CTH / Cystathionase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
Viewing 1-25 of 83 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).