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Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.
Gene Name: | extended synaptotagmin-like protein 1 |
Synonyms: | ESYT1, E-Syt1, Extended synaptotagmin-1, KIAA0747, MBC2, FAM62A |
Target Sequences: | NM_015292 NP_056107.1 Q9BSJ8 |
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