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Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Gene Name: | small proline-rich protein 1B |
Synonyms: | SPRR1B, 14.9 kd pancornulin, 14.9 kDa pancornulin, CORNIFIN, GADD33, SPR-IB, Small proline-rich protein IB, SPRR1, Cornifin B, Cornifin-B, Small proline-rich protein 1B |
Target Sequences: | NM_003125 NP_003116.2 P22528 |
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