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Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Gene Name: | cleavage and polyadenylation specific factor 1, 160kDa |
Synonyms: | CPSF1, CPSF 160 kDa subunit, CPSF160, HSU37012, P/cl.18 |
Target Sequences: | NM_013291 NP_037423.2 Q10570 |
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