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Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.
Gene Name: | TAP binding protein-like |
Synonyms: | TAPBPL, TAP binding protein related, TAPBP-R, TAP binding protein-like, Tapasin-related protein, TAPASIN-R, TAPBPR, TAP-binding protein-like, Tapasin-like |
Target Sequences: | NM_018009 NP_060479.3 Q9BX59 |
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