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TAPBP / Tapasin

TAP binding protein (tapasin)

TAPBP / Tapasin is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene Name: TAP binding protein (tapasin)
Synonyms: TAPBP, TAP binding protein (tapasin), TAPA, TAP-associated protein, TAP-binding protein, TPN, NGS17, NGS-17, Tapasin, TPSN
Target Sequences: NM_003190 NP_003181.3 O15533

Publications (1)

1
Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clusters. Femmy C Stempels, Muwei Jiang , Harry M Warner , Magda-Lena Moser, Maaike H Janssens, Sjors Maassen, Iris H Nelen, Rinse de Boer, William F Jiemy, David Knight, Julian Selley, Ronan O'Cualain, Maksim V Baranov, Thomas C Q Burgers, Roberto Sansevrino, Dragomir Milovanovic, Peter Heeringa, Matthew C Jones, Rifka Vlijm, Martin Ter Beest, Geert van den Bogaart. The Journal of cell biology. 2023 July;222: [Full Text Article] [PubMed:37200023] [PMC:PMC10200693] Related Antibodies: LS-C331792.

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Antibodies (25)
Primary (25)
TAPBP / Tapasin (25)
Human (25)
Mouse (9)
Rat (6)
Bovine (7)
Chimpanzee (9)
Monkey (3)
Pig (6)
Sheep (9)
IHC (8)
IHC-P (4)
WB (25)
ELISA (7)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (25)
Product Group
IHCPlus (1)
IgG (13)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (11)
aa42-70 (7)
aa307-356 (4)
aa35-84 (4)
aa359-408 (4)
No (24)
Yes (1)
TAPBP / Tapasin Antibody - Immunohistochemistry of paraffin-embedded human stomach using TAPBP antibody at dilution of 1:200 (x400 lens)
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Mouse, Sheep, Rat, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Mouse, Sheep, Rat, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Mouse, Sheep, Rat, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - Lane 1: MWM, Lane 2: A431 Lysate
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Bovine, Human
IP, WB
Unconjugated
50 µg/$349; 200 µg/$541
TAPBP / Tapasin Antibody - Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa307-356) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
TAPBP / Tapasin Antibody - Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa307-356) (HRP) Antibody
Sheep, Bovine, Pig, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa307-356) (Biotin) Antibody
Sheep, Bovine, Pig, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - Anti-TAPBP / Tapasin antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa307-356) (FITC) Antibody
Sheep, Bovine, Pig, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - Immunohistochemistry of paraffin-embedded rat liver using TAPBP antibody at dilution of 1:100 (40x lens).
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
TAPBP / Tapasin Antibody - 1:100 staining rat colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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TAPBP / Tapasin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa359-408) Antibody
Human
WB
Unconjugated
100 µl/$424
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa359-408) (HRP) Antibody
Mouse, Sheep, Bovine, Pig, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa359-408) (Biotin) Antibody
Mouse, Sheep, Bovine, Pig, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - TAPBP / Tapasin antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa359-408) (FITC) Antibody
Mouse, Sheep, Bovine, Pig, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
TAPBP / Tapasin Antibody - TAPBP Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The TAPBP antibody detected the TAPBP protein (arrow).
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TAPBP / Tapasin Rabbit anti-Human Polyclonal (aa42-70) Antibody
Human
WB
Unconjugated
400 µl/$393
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).