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Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Gene Name: | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | TAF1A, SL1, 48kD subunit, TBP-associated factor 1A, TAFI48, MGC:17061, Transcription factor SL1, RAFI48, SL1 |
Target Sequences: | NM_005681 NP_005672.1 Q15573 |
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