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TAF15 is a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
Synonyms: | TAF15, RBP56, RBP56/CSMF fusion, RNA-binding protein 56, TAFII68, TAF2N, TBP-associated factor 15, HTAFII68, TAF(II)68 |
Target Sequences: | NM_003487 NP_003478.1 Q92804 |
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