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This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Gene Name: | tachykinin receptor 2 |
Family/Subfamily: | GPCR , Tachykinin |
Synonyms: | TACR2, Neurokinin 2 receptor, NK-2 receptor, Neurokinin A receptor, NK2, NK2R, Tachykinin receptor 2, Substance-K receptor, NK-2R, SK receptor, SKR, TAC2R, NKNAR, Substance K receptor |
Target Sequences: | NM_001057 NP_001048.2 P21452 |
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