TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2

TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants.

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Products

ELISA Kits (4)

Type

Custom (2)

Sandwich (2)

Target

TAB2 (4)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

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Human TAB2 (Sandwich ELISA) ELISA Kit - LS-F12690

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse TAB2 (Custom ELISA) ELISA Kit - LS-F19806

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat TAB2 (Custom ELISA) ELISA Kit - LS-F19805

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human TAB2 (Sandwich ELISA) ELISA Kit - LS-F33837

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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