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SYT1 / Synaptotagmin

synaptotagmin I

May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2.

Gene Name: synaptotagmin I
Family/Subfamily: Synaptotagmin , Not assigned-Other
Synonyms: SYT1, SYT, SVP65, Synaptotagmin, Synaptotagmin 1, SytI, Synaptotagmin I, Synaptotagmin-1
Target Sequences: NM_005639 NP_005630.1 P21579

Publications (2)

1
Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors. Yu Liu , Miao Yu , Xuanze Shang, My Hong Hoai Nguyen, Shanmuganathan Balakrishnan, Rachel Sager, Huaiyu Hu. Scientific reports. 2020 May;10:7795. [Full Text Article] [PubMed:32385361] [PMC:PMC7210881] Related Antibodies: LS-B5899.
2
16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis. Danielle L Tomasello, Jiyoon L Kim, Yara Khodour, Jasmine M McCammon, Maya Mitalipova, Rudolf Jaenisch, Anthony H Futerman, Hazel Sive. iScience. 2022 January;25:103551. [Full Text Article] [PubMed:34984324] [PMC:PMC8693007] Related Antibodies: LS-B12889.

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ELISA Kits (3)
Sandwich (2)
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SYT1 / Synaptotagmin (3)
Mouse (3)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (1)
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Plasma (3)
Serum (3)
Tissue Homogenates (1)
SYT1 / Synaptotagmin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SYT1 / Synaptotagmin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
SYT1 / Synaptotagmin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).