Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
SUR2 / ABCC9 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants.
Gene Name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
Family/Subfamily: | Transporter , ATP-binding cassette - ABCC/MRP |
Synonyms: | ABCC9, ATFB12, CANTU, CMD1O, ABC37, Sulfonylurea receptor, Sulfonylurea receptor 2, SUR2, Sulfonylurea receptor 2A |
Target Sequences: | NM_005691 NP_005682.2 O60706 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.