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STX5 / Syntaxin 5 is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | syntaxin 5 |
Synonyms: | STX5, SED5, STX5A, Syntaxin 5A, Syntaxin-5, Syntaxin 5 |
Target Sequences: | NM_003164 NP_003155.2 Q13190 |
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