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STX1B / Syntaxin 1B belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested.
Gene Name: | Syntaxin 1b |
Family/Subfamily: | Syntaxin/epimorphin , Not assigned-Other |
Synonyms: | STX1B |
Target Sequences: | M95735 NP_443106.1 P61266 |
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