STAT5B

signal transducer and activator of transcription 5B

STAT5B is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

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Products

ELISA Kits (14)

Type

Cell-Based (1)

Cell-Based Phosphorylation (3)

Custom (4)

DNA Binding (1)

DNA Binding Phosphorylation (1)

Sandwich (4)

Target

STAT5B (14)

Reactivity

Human (8)

Mouse (8)

Rat (8)

Pig (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (4)

96-Well Strip Plate (8)

Publications

No (14)

Sample Type

Adherent Cell Cultures (4)

Cell Lysates (2)

Cell Supernatant (1)

Nuclear Lysates (2)

Plasma (3)

Serum (3)

Tissue Homogenates (1)

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Mouse/Human/Rat STAT5B (DNA-Binding ELISA) ELISA Kit - LS-F820

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Human STAT5B (Sandwich ELISA) ELISA Kit - LS-F35257

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$579

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Mouse/Human/Rat Phospho-STAT5B (Ser725/730) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1379

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat STAT5B (Cell-Based ELISA) ELISA Kit - LS-F2331

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human STAT5B (Sandwich ELISA) ELISA Kit - LS-F12670

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat STAT5B (Sandwich ELISA) ELISA Kit - LS-F38703

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse STAT5B (Sandwich ELISA) ELISA Kit - LS-F75001

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Rat STAT5B (Custom ELISA) ELISA Kit - LS-F20412

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Bovine STAT5B (Custom ELISA) ELISA Kit - LS-F20413

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse STAT5B (Custom ELISA) ELISA Kit - LS-F20414

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Pig STAT5B (Custom ELISA) ELISA Kit - LS-F20415

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse/Human/Rat Phospho-STAT5B (Ser731) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F916

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

Select

Mouse/Human/Rat Phospho-STAT5B (Ser731) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1104

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human/Rat Phospho-STAT5B (Tyr694) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1627

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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