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Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
Gene Name: | stromal antigen 1 |
Synonyms: | STAG1, Cohesin subunit SA-1, SA-1, SCC3 homolog 1, SCC3A, Stromal antigen 1, SA1 |
Target Sequences: | NM_005862 NP_005853.2 Q8WVM7 |
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