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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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STAB1
stabilin 1
STAB1 is a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.
| Gene Name: | stabilin 1 |
| Synonyms: | STAB1, FEEL-1, KIAA0246, FELE-1, MS-1 antigen, STAB-1, Stabilin 1, Stabilin-1, CLEVER-1, FEEL1, FEX1 |
| Target Sequences: | NM_015136 NP_055951.2 Q9NY15 |
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