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ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.
| Gene Name: | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| Synonyms: | ST8SIA1, Alpha-2,8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, GD3S, SIAT8A, Sialytransferase St8Sia I, ST8SiaI, Sialyltransferase 8A, SIAT8, SIAT8-A |
| Target Sequences: | NM_003034 NP_003025.1 Q92185 |
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