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ST6GAL1 is a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.
Gene Name: | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
Family/Subfamily: | Glycosyltransferase |
Synonyms: | ST6GAL1, Alpha 2,6-ST 1, Sialyltransferase 1, SIAT1, ST6Gal I, ST6GalI, ST6N, B-cell antigen CD75, CD75 |
Target Sequences: | NM_173216 NP_775323.1 P15907 |
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