SSTR2

somatostatin receptor 2

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

SSTR2 (6)

Publications

No (6)

Tag

GST, N-terminus (2)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

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Human SSTR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78907

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

20 µg/$150

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Human SSTR2 Protein (Recombinant GST, N-terminus) (aa316-369) - LS-G60217

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SSTR2 Protein (Recombinant GST, N-terminus) (aa1-60) - LS-G60218

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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SSTR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99325

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

100 µg/$494

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Human SSTR2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67000

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

20 µg/$1,107

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Human SSTR2 Protein (Recombinant His, N-Terminal) (Ser31-Leu218) - LS-G133016

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.8kDa

Price:

10 µg/$279; 50 µg/$432; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,441

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