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Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Gene Name: | signal recognition particle 9kDa |
Synonyms: | SRP9, ALURBP |
Target Sequences: | NM_003133 NP_003124.1 P49458 |
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