SREBF1 / SREBP-1

sterol regulatory element binding transcription factor 1

SREBF1 / SREBP-1 is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene.

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Products

ELISA Kits (10)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Sandwich (8)

Target

SREBF1 / SREBP-1 (10)

Reactivity

Human (3)

Rat (3)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (8)

Publications

No (10)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human/Rat Phospho-SREBF1 / SREBP-1 (Ser439) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1744

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human/Rat SREBF1 / SREBP-1 (Cell-Based ELISA) ELISA Kit - LS-F2323

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F52669

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

7.8 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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Rat SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F54009

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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Chicken SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48198

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

3.906 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48199

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48200

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48201

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48202

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

3.906 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Sheep SREBF1 / SREBP-1 (Sandwich ELISA) ELISA Kit - LS-F48203

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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