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SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Steroid 5-alpha reductase 2 is a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. This isoform is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
| Gene Name: | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| Synonyms: | SRD5A2, 5 alpha-SR2, S5AR 2, Type II 5-alpha reductase, SR type 2, Steroid 5-alpha-reductase 2 |
| Target Sequences: | NM_000348 NP_000339.2 P31213 |
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Products
Proteins
(1)
Type
Recombinant
(1)
Target
SRD5A2
(1)
Publications
No
(1)
Tag
GST, N-terminus
(1)
Species
Human
(1)
Source
Wheat Germ Extract
(1)
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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