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SPTLC1 / HSN1
serine palmitoyltransferase, long chain base subunit 1
Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.
| Gene Name: | serine palmitoyltransferase, long chain base subunit 1 |
| Synonyms: | SPTLC1, HSAN1, HLCB1, HSAN, LCB1, HSN1, LCB 1, Serine palmitoyltransferase 1, SPTI, SPT 1, Serine C-palmitoyltransferase, LBC1, SPT1 |
| Target Sequences: | NM_006415 NP_006406.1 O15269 |
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Antibodies
(44)
Type
Primary
(44)
Target
SPTLC1 / HSN1
(44)
Reactivity
Human
(44)
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(24)
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(12)
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(6)
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(6)
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(6)
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(3)
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(7)
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(6)
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(4)
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(7)
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(14)
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(9)
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(44)
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(15)
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(3)
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rabbit
(44)
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(1)
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IgG
(30)
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polyclonal pc
(44)
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(1)
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(3)
Azide-free
(2)
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(5)
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(1)
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(1)
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(5)
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(5)
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(3)
Unconjugated
(21)
Epitope
aa143-473
(8)
aa26-57
(7)
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(6)
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(4)
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(4)
411-460 aa, C-terminal
(1)
C-Terminus
(1)
aa138-154
(1)
aa37-310
(1)
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(1)
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(1)
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(1)
Publications
No
(44)
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (HRP) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (Biotin) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa254-303) (FITC) Antibody
Rabbit, Mouse, Guinea pig, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa50-100) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa26-57) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa37-310) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SPTLC1 / HSN1 Rabbit anti-Mouse Polyclonal (aa143-473) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa138-154) Antibody
Rabbit, Sheep, Bovine, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa444-473) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µg/$466
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa26-57) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa26-57) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (411-460 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa423-473) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
SPTLC1 / HSN1 Rabbit anti-Human Polyclonal (aa405-437) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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of 44
product results
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