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SPR

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

SPR is an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Gene Name: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms: SPR, SDR38C1, Sepiapterin reductase
Target Sequences: NM_003124 NP_003115.1 P35270

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
SPR (9)
No (9)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
SPR Protein - Recombinant Sepiapterin Reductase By SDS-PAGE
Select
E. coli
His-GST
58.0 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
SPR Protein - Recombinant  Sepiapterin Reductase By SDS-PAGE
Select
E. coli
His-T7
31.6 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SPR Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
SPR Protein - 12.5% SDS-PAGE of human SPR stained with Coomassie Blue
Select
Wheat Germ Extract
GST
54.4 kDa
10 µg/$479; 25 µg/$670
SPR Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SPR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$150
SPR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
100 µg/$494
SPR Protein - Purified recombinant protein SPR was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
27.9 kDa
20 µg/$1,107
SPR Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His, N-terminus
32.0 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).