SPPL2B

signal peptide peptidase like 2B

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.

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Products

Antibodies (14)

Type

Primary (14)

Target

SPPL2B (14)

Reactivity

Human (14)

Bovine (3)

Chimpanzee (3)

Application

IHC (4)

IHC-P (4)

WB (10)

ELISA (4)

IF (1)

Peptide-ELISA (2)

Host

rabbit (14)

Isotype

IgG (8)

Clonality

polyclonal pc (14)

Format

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (5)

Epitope

aa53-102 (4)

aa93-142 (4)

aa126-160 (1)

aa196-229 (1)

Publications

No (14)

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SPPL2B Antibody LS-C681453

Antibody:

SPPL2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2B Antibody (HRP) LS-C681451

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2B Antibody (Biotin) LS-C681454

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPPL2B Antibody (FITC) LS-C681450

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SPPL2B Antibody (aa93-142) LS-C80685

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa93-142) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SPPL2B Antibody (aa93-142, HRP) LS-C447249

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa93-142) (HRP) Antibody

Reactivity:

Bovine, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SPPL2B Antibody (aa93-142, Biotin) LS-C447247

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa93-142) (Biotin) Antibody

Reactivity:

Bovine, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SPPL2B Antibody (aa93-142, FITC) LS-C447248

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa93-142) (FITC) Antibody

Reactivity:

Bovine, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SPPL2B Antibody (aa196-229) LS-C392735

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa196-229) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

SPPL2B Antibody (aa126-160) LS-C392784

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa126-160) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

SPPL2B Antibody (aa53-102) LS-C201482

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa53-102) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SPPL2B Antibody (aa53-102, HRP) LS-C447246

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa53-102) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SPPL2B Antibody (aa53-102, Biotin) LS-C447244

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa53-102) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SPPL2B Antibody (aa53-102, FITC) LS-C447245

Antibody:

SPPL2B Rabbit anti-Human Polyclonal (aa53-102) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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