SPOP

speckle-type POZ protein

Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.

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Products

Antibodies (24)

Proteins (14)

ELISA Kits (8)

Type

Over-Expression Lysate (10)

Primary (24)

Recombinant (4)

Sandwich (8)

Target

SPOP (46)

Reactivity

Human (24)

Mouse (10)

Rat (8)

Bovine (3)

Chicken (4)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (4)

Hamster (3)

Horse (3)

Monkey (4)

Orangutan (3)

Pig (3)

Porcine (1)

Rabbit (4)

Sheep (1)

Xenopus (3)

Zebrafish (4)

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Application

IHC (7)

IHC-P (1)

WB (20)

ELISA (15)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (1)

Isotype

IgG (20)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (23)

Clone

3E2 (1)

Format

96-Well Strip Plate (8)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (13)

Epitope

aa86-115 (6)

C-Terminus (4)

aa74-107 (1)

Publications

No (46)

Sample Type

Plasma (2)

Serum (2)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (11)

Species

Human (9)

Source

293T Cells (5)

E. coli (1)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

SPOP Antibody (C-Terminus) LS-C81545

Antibody:

SPOP Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SPOP Antibody (C-Terminus, HRP) LS-C453654

Antibody:

SPOP Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SPOP Antibody (C-Terminus, Biotin) LS-C453652

Antibody:

SPOP Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SPOP Antibody (C-Terminus, FITC) LS-C453653

Antibody:

SPOP Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Orangutan, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SPOP Antibody LS-C376664

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPOP Antibody (HRP) LS-C376670

Antibody:

SPOP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPOP Antibody (Biotin) LS-C376669

Antibody:

SPOP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

SPOP Antibody (FITC) LS-C376667

Antibody:

SPOP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SPOP Antibody LS-C109401

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$450

Select

SPOP Antibody LS-C802612

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

Select

SPOP Antibody LS-C755360

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SPOP Antibody LS-C743348

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SPOP Antibody LS-C813554

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

SPOP Antibody (clone 3E2) LS-C198555

Antibody:

SPOP Mouse anti-Human Monoclonal (3E2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$335

Select

SPOP Antibody (aa86-115) LS-C325345

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SPOP Antibody (aa86-115, Biotin) LS-C241202

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SPOP Antibody (aa86-115, FITC) LS-C241203

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SPOP Antibody (aa86-115, APC) LS-C241201

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SPOP Antibody (aa86-115, PE) LS-C241205

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

SPOP Antibody (aa86-115, Azide-free, HRP) LS-C248240

Antibody:

SPOP Rabbit anti-Human Polyclonal (aa86-115) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

SPOP Antibody LS-C780215

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$357

Select

SPOP Antibody LS-C349276

Antibody:

SPOP Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

SPOP Antibody LS-C747292

Antibody:

SPOP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

SPOP Antibody (aa74-107) LS-C344692

Antibody:

SPOP Rabbit anti-Zebrafish Polyclonal (aa74-107) Antibody

Reactivity:

Zebrafish, Mouse

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human SPOP Protein (Recombinant GST, N-terminus) (aa301-374) - LS-G60708

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-25 of 46 product results

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