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SPINT1 / HAI-1 is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
Gene Name: | serine peptidase inhibitor, Kunitz type 1 |
Family/Subfamily: | Serine Protease Inhibitor , not assigned-Serine Protease Inhibitor |
Synonyms: | SPINT1, HAI1, MANSC2, HAI, HAI-1 |
Target Sequences: | NM_003710 NP_003701.1 O43278 |
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