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SPG20 / SPARTIN

spastic paraplegia 20 (Troyer syndrome)

SPG20 / SPARTIN is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).

Gene Name: spastic paraplegia 20 (Troyer syndrome)
Synonyms: SPG20, KIAA0610, Spastic paraplegia 20 protein, Spartin, TAHCCP1
Target Sequences: AB011182 BAA25536.1 Q8N0X7

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Proteins (12)
Over-Expression Lysate (8)
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SPG20 / SPARTIN (12)
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293T Cells (4)
HEK 293 Cells (8)
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HEK 293 Cells
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72.7 kDa
20 µg/$1,107
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$1,107
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$1,107
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$1,107
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
100 µg/$494
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$215
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$215
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$215
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
72.7 kDa
20 µg/$150
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
100 µg/$710
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
100 µg/$710
SPG20 / SPARTIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
72.7 kDa
100 µg/$710
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).