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SPECC1 / CYTSB
sperm antigen with calponin homology and coiled-coil domains 1
The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Gene Name: | sperm antigen with calponin homology and coiled-coil domains 1 |
| Synonyms: | SPECC1, CYTSB, Cytospin-B, HCMOGT-1, Structure protein NSP5a3b, Structure protein NSP5b3a, Structure protein NSP5b3b, Structure protein NSP5a3a, HCMOGT1, NSP, NSP5, Nuclear structure protein 5, Sperm antigen HCMOGT-1 |
| Target Sequences: | NM_001033554 NP_001028726.1 Q5M775 |
Publications (2)
1
NSP 5a3a: a potential novel cancer target in head and neck carcinoma. D'agostino L, Giordano A. Oncotarget. 2010 1:423-35. (WB; Human)
[PubMed:21311098]
[PMC:PMC3248119]
2
A novel dual signaling axis for NSP 5a3a induced apoptosis in head and neck carcinoma. D'Agostino L, Giordano A. Oncotarget. 2011 2:1055-74. (ICC, WB, IP; Human)
[PubMed:22170762]
[PMC:PMC3282067]
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(28)
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(5)
Type
Over-Expression Lysate
(2)
Primary
(28)
Recombinant
(3)
Target
SPECC1 / CYTSB
(33)
Reactivity
Human
(28)
Mouse
(9)
Chimpanzee
(3)
Monkey
(3)
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(3)
Application
IHC
(11)
IHC-P
(11)
WB
(28)
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(1)
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(1)
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(1)
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(2)
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rabbit
(28)
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(2)
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IgG
(3)
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polyclonal pc
(28)
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APC
(1)
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(1)
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(4)
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(1)
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(1)
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(2)
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(2)
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(2)
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(2)
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(2)
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(1)
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(10)
Epitope
aa961-1063
(8)
aa1-100
(5)
aa200-300
(5)
aa148-197
(4)
Internal
(2)
aa125-175
(1)
aa450-500
(1)
aa705-733
(1)
Publications
No
(33)
Tag
GST, N-terminus
(1)
His
(1)
His-T7
(1)
Myc-DDK (Flag)
(2)
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Human
(3)
Mouse
(1)
Source
293T Cells
(1)
E. coli
(2)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(1)
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa705-733) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa200-300) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa200-300) (Biotin) Antibody
Human
IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa200-300) (DY650) Antibody
Human
IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa200-300) (DY488) Antibody
Human
IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa200-300) (DY550) Antibody
Human
IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa1-100) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa1-100) (Biotin) Antibody
Human
IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa1-100) (DY650) Antibody
Human
IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa1-100) (DY488) Antibody
Human
IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa1-100) (DY550) Antibody
Human
IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa450-500) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa125-175) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$792; 2 ml/$1,030; 5 ml/$1,803
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$366; 200 µl/$432; 500 µl/$683; 1 ml/$842; 2 ml/$1,088; 5 ml/$1,941
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (Cy3) Antibody
Mouse, Human
WB
Cy3 Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (APC, Cy7) Antibody
Mouse, Human
WB
APC, Cy7 Conjugated
100 µl/$543; 200 µl/$732; 500 µl/$1,268; 1 ml/$1,585; 2 ml/$2,219; 5 ml/$4,159
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
SPECC1 / CYTSB Rabbit anti-Mouse Polyclonal (aa961-1063) (APC) Antibody
Mouse, Human
WB
APC Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$649
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$649
SPECC1 / CYTSB Rabbit anti-Human Polyclonal (aa148-197) Antibody
Human
WB
Unconjugated
100 µl/$424
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