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SP7 / Osterix

Sp7 transcription factor

SP7 / Osterix is a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

Gene Name: Sp7 transcription factor
Family/Subfamily: Transcription Factor
Synonyms: SP7, OI11, OI12, Osterix, Sp7 transcription factor, Transcription factor Sp7, Zinc finger protein osterix, OSX
Target Sequences: NM_152860 NP_690599.1 Q8TDD2

Publications (1)

1
Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. Rashid H, Ma C, Chen H, Wang H, Hassan MQ, Sinha K, de Crombrugghe B, Javed A. Connective tissue research. 2014 1:83-7. (WB; Human) [Full Text Article] [PubMed:25158187] [PMC:PMC4269247] Related Antibodies: LS-C139215.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SP7 / Osterix (4)
No (4)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
SP7 / Osterix Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44.8 kDa
20 µg/$150
SP7 / Osterix Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SP7 / Osterix Protein - 12.5% SDS-PAGE of human SP7 stained with Coomassie Blue
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Wheat Germ Extract
GST
73.9 kDa
10 µg/$479; 25 µg/$670
SP7 / Osterix Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
44.8 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).