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SP7 / Osterix is a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.
Gene Name: | Sp7 transcription factor |
Family/Subfamily: | Transcription Factor |
Synonyms: | SP7, OI11, OI12, Osterix, Sp7 transcription factor, Transcription factor Sp7, Zinc finger protein osterix, OSX |
Target Sequences: | NM_152860 NP_690599.1 Q8TDD2 |
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