Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells.
Gene Name: | SRY (sex determining region Y)-box 17 |
Family/Subfamily: | Transcription factor |
Synonyms: | SOX17, Transcription factor SOX-17, VUR3 |
Target Sequences: | NM_022454 NP_071899.1 Q9H6I2 |
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